5 Best Agmatine Supplements – 2017 Reviews and Top Picks

Agmatine is known in the body-building world as a muscle-pump enhancer. The real thing, however, is that agmatine also induces pain tolerance, fast muscle recovery, improves focus, cures depression and it promotes well-being.

Whatever purpose you would want to use agmatine for, you may have difficulty selecting the best agmatine supplement that suits your particular needs. With this list, we compile the most excellent products that promise the full benefits of agmatine.

Best Agmatine Supplement


Our Top 5 Best Agmatine Supplement

Bulk Supplements Pure Agmatine Sulfate Powder is guaranteed pure agmatine, but it actually comes in salt-like form. If you are the likes of those who want to incorporate their supplements with fruit shakes or juice, then this powder is definitely the good choice for you.

It tastes bitter and some people don’t like the smell either. But lots of them who tried it attest to the fact that this product is indeed pure agmatine.

AgmaSet is formerly known as Neurofencine. Perhaps because of the latest scientific breakthroughs which confirm the company founders’ prior research about agmatine, it was rebranded to reflect the name of its key component – the G-agmatine.

The G-agmatine is designed particularly for nerve health. People suffering from nerve problems and neuropathic pain trust this product because of the company’s reputation for manufacturing supplements backed up by sound research and clinical trials.

best agmatine supplement

This comes in 60 servings per bottle, and each serving contains 500 mg. This is pretty cost-wise for those who need 1 gram a day because one bottle, which costs less than 20 bucks, can last a month.

Ai Sports Company has good reputation for customer service in case of problems. This supplement can be taken simultaneously with other intensive training energy-enhancer such as citrulline mallate.

Olympian Labs Agmatine Sulfate Supplement is worth its cost because it does not only boost one’s nitric oxide levels, it also aids in recuperation and improved health. It is like double-edged sword actually.

Even for those who do not work out, this may be a good substitute for reducing anxiety and nerve pain. Agmatine sulfate is proven to reduce addiction withdrawal symptoms without having side effects.

The 360NitroDrive is a caffeine-free pre-workout supplement in powdered form. It is free of stimulants that may cause sleep deprivation if you are working out at night.

If you are a tough beast looking for a multivitamin and pump-booster supplement at the same time, this one may be suitable for you. It contains other major ingredient such as Vitamin C to boost your immune system and Vitamin B12 to aid in fatigue relief and DNA formation.

Reviews Of The Best Agmatine

Best Agmatine Supplement

Packed in foil zip pouches, this grainy supplement dissolves easily in water. You may find it a necessity, though, to mix this with any flavored drink just to mask its repulsive bitter taste.

Each serving contains 750mg of pure agmatine sulfate, of which you can have a steady supply by ordering in bulks of 100g, 500g or 1000g. It may not come in fine powder as imagined, but with its crystalline form, you are rest assured that there are no fillers added.

Some people who used this complained of dry mouth while working out, which is just as expected, because extreme physical activity certainly dries out any one. Unlike other two-in-one or multi-supplements, this pure agmatine sulfate powder is not combined with other substance that provides sufficient hydration.

This supplement is effective not only in boosting energy levels during workout, it also alleviates soreness and fast muscle recovery. However, individuals who have headache reactions to agmatine must find another alternative.


  • No other additives or fillers
  • ​Good price
  • ​Easily soluble
  • Crystalline form


  • Bitter taste
  • Becomes clumpy when moist

Best Agmatine Supplement

One bottle contains 60 capsules and each serving consists 890mg of G-agmatine. It is gluten-free and it has no other additives.

G-agmatine is Gilad&Gilad’s own brand of agmatine. It is a substance manufactured by the company itself and protected by patent.

The wondrous effect of agmatine to neuropathic pain is backed by scientific research and clinical trials. It was the founders of Gilad&Gilad, Dr. Gilad and Dr. Gilad, that led the collaborative research investigating the properties of agmatine.

In the study, agmatine is found capable of alleviating pain and improving the well-being of persons suffering from chronic neuropathic pain. Thus, the company, which specializes in nerve health, designed the dietary agmatine for this purpose.

This nutriceutical is not only limited to treating nerve traumas or damaged cells. People who suffer from anxiety, withdrawal symptoms and nerve problem can help recover their health by taking this supplement.

People who tried it find it as a good medication alternative in reducing diabetic neuropathy. Others have observed similar effects and its endorphin-boosting properties as well.


  • High-quality type of agmatine
  • Backed by scientific research
  • ​Company’s good reputation
  • Proven to be safe and effective


  • Expensive
  • Designed only for neuropathy and nerve issues

Best Agmatine Supplement

Like the supplements mentioned above, this product is also pure agmatine sulfate. But the fact that it doesn’t hurt your pocket that much is what sets it apart.

With one bottle, you can have an ample supply of nitric oxide enhancer for about 30 days, that is, as long as you stay with 1000mg or 4 capsules each day. Actually, you may not have to worry about high-dosage levels because agmatine sulfate is considered non-toxic, although information about its side effects with large doses is scarce.

The recommended dosage is 250mg to 1g. A dose up to 2.5g is still relatively safe but intake beyond 1.5 g may cause gastrointestinal discomfort and mild diarrhea.

Ai Sports Agmatine Sulfate dilates the blood vessels for improved blood flow and oxygen delivery in the body. Thus, this body processes translate to increased energy levels and endurance.


  • Pump-enhancing properties
  • Improves blood circulation
  • ​Synergistic effect with citrulline mallate and growth hormones
  • Not expensive


  • Contains gelatin

Best Agmatine Supplement

Two capsules of this supplement per day is an effective dietary regimen for individuals who want to improve their frame of mind and wellbeing. For those who engage in strenuous physical exercise, 30 to 60 minutes before workout is advised.

One bottle contains 30 servings with 500mg agmatine sulfate each. More than 15 bucks per bottle is quite expensive for those who need more than 1g per day, but its quality and reputation for effectiveness especially with mood enhancement and chronic pain is definitely worth the price.

Obviously, this supplement is manufactured to support workout goals and sports nutrition. People who used this product, however, find it as a good alternative for their pain medications.

While dietary supplements such as agmatine sulfate may not replace pain-relief tablets, their ability to assuage pain symptoms is beneficial. In fact, one research study, which involves 61 individuals suffering from lower back pain, shows that significant doses of this supplement for over 10 days improved their conditions.

Other individuals who used this supplement report of improved RSD-related symptoms, better sleep, increased appetite and lower anxiety levels. For those who lift weights like beasts, this may be a good quality choice but not at a lowest price.


  • Nootropic effects
  • Pure agmatine sulfate
  • Gluten-free
  • Allergen-free


  • Expensive

Best Agmatine Supplement

360NitroDrive is an all-in-one supplement for greater work-out performance. One bottle consists of 20 servings and each serving contains 750mg of agmatine.

Agmatine sulfate blends together with two other significant supplements for intense training sessions: Hydromax (200mg) and Nitrosigine (750mg). Nitrosigine keep energy levels high up to six hours while hydromax keeps athletes and bodybuilders from being dehydrated.

It also contains taurine (1000mg) which is essential in any energy-depleting exercise or activity. Taurine strengthens your heart and keep your hearbeat regulated.

With 1000mg creatine HCL, the DNA damage that may be induced by intense exercise is reduced. Creatine HCL is soluble and it is easily absorbed in your system.

It also contains citrulline mallate (3000mg), which is a great ingredient in any workout or athlete supplement. It is an amino acid compound which combats fatigue and keeps you motivated.

This substance helps in increasing the effect of nitric oxide in blood vessel dilation and blood low. It reduces exhaustion during intense activity.


  • Contains powerful ingredients for high-intensity workouts
  • Complete package of important supplements in one
  • ​CMGP-certified manufacturing process
  • ​Not bitter-tasting
  • Stimulant-free


  • Expensive
  • Too much supplements for mild exercise and workouts

What Is Agmatine?

Agmatine is an arganine metabolite. But it differs from arganine in a way that the latter converts directly into nitric oxide, while the former inhibits the enzymes that synthesize nitric oxide.

What Are The Benefits Of Agmatine

Best Agmatine Supplement
  • Increases testosterone (luteinizing hormone) and prevents erectile dysfunction by dilating the blood vessels
  • Has curative effect on depression (Unlike other anti-depressants, which works to increase serotonin levels, agmatine treats depression by both increasing serotonin levels with other agents and remission of depression by itself)
  • ​Prevents seizures
  • ​Cures drug addictions and reduce withdrawal symptoms
  • ​Reduced perception of pain
  • ​Not neurotoxic
  • ​Stress reduction
  • ​Mental clarity
  • ​Regulates insulin
  • ​Maintain healthy blood pressure levels
  • ​Potential to prevent stroke and reduce brain damage caused by a stroke
  • Good for those who have difficulty gaining weight, because it induces appetite even when full

Side Effects Of Agmatine Supplements

best agmatine supplement
  • Mild gastrointestinal discomfort
  • ​Increased appetite
  • ​Scarcity of research and information about agmatine’s toxicity levels (What is certain, though, is research reveals that regular use of Agmatine up to 5 years is safe)
  • ​May not be recommended for persons who have problems with low blood pressure or hypotension
  • Not recommended for pregnant and lactating women


Best Agmatine Supplement
  • Do not take along with dietary protein because it will slow the absorption of agmatine and thereby lessen its effects on the body
  • Safe dosage is up to 2.6 grams per day.
  • ​It may not go well with l-arginine, l-citrulline, yohimbine, D-aspartic acid, and creatinine
  • To increase benefits, it is good to take Agmatine along with growth hormone supplements and with carbohydrates


Best Agmatine Supplement

We rated BulkSupplements Agmatine as the top contender in this review. The quality that stands out is its versatility.

The fact that it comes in powder means that you can control its dosage. Unlike the ones in capsule form, which contains 500mg each, you can reduce the powdered form to the amount or dosage you prefer.

You can spread out your daily intake by dividing the sachet in three parts (250mg each). In this way, you can safely take agmatine simultaneously with other supplements, whether as pre-workout supplement or as neuropathic pain reliever.

But pure agmatine is definitely worth on its own because it offers all the benefits of a nutraceutical. With this as the only active ingredient, you get the full benefits of the best agmatine supplement without worrying about the effects of other additives in your system.

Luke Cafferty

Luke Cafferty is a fitness junkie, personal trainer and blogger. He's passionate about living a healthy lifestyle and maintaining a strong and well rounded physique, while inspiring you to do the same.

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